Thermo Fisher Scientific DVL1 Polyclonal Antibody
Rabbit polyclonal antibody targeting human DVL1 (Dishevelled 1). Validated for Western blot at 5–7 µg/mL. Reacts with human, mouse, rat, and primate samples. Supplied as liquid, unconjugated, purified by Protein A, and stored in PBS with BSA and sodium...
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Applications
- Western Blot (WB): Tested dilution 5–7 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Non-human primate, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A portion of amino acids 70–120 of human DVL1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2540931 |
Target Information
DVL1, the human homolog of the Drosophila dishevelled gene (dsh), encodes a cytoplasmic phosphoprotein that regulates cell proliferation. It acts as a transducer molecule for developmental processes, including segmentation and neuroblast specification. DVL1 is a candidate gene for neuroblastomatous transformation. The Schwartz-Jampel syndrome and Charcot-Marie-Tooth disease type 2A have been mapped to the same region as DVL1, and the phenotypes of these diseases may be consistent with defects that could arise from aberrant expression of a DVL gene during development.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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