Thermo Fisher Scientific ABCG1 Polyclonal Antibody
ABCG1 단백질을 인식하는 Rabbit Polyclonal Antibody로, Western Blot과 IHC에 적합합니다. 합성 펩타이드(aa 350–400)를 항원으로 사용하였으며, Lyophilized 형태로 제공됩니다. 인체 시료에 반응하며 연구용으로만 사용됩니다.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:300–1:2,000 | - |
| Immunohistochemistry (IHC) | 1:300–1:2,000 | - |
| Miscellaneous PubMed (Misc) | - | View 2 publications |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / Ig |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from aa region 350–400 of human ABCG1 conjugated to an immunogenic carrier protein |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not Determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C avoiding freeze/thaw cycles. Glycerol (1:1) may be added for stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
Specificity of this antibody: ABCG1
Target Information
ATP-binding cassette (ABC) transporter genes regulate dietary cholesterol retention in the body.
ABCG1 (ABC8) is expressed on the cell surface and in intracellular compartments of cholesterol-laden macrophages.
It is induced in monocyte-derived macrophages during cholesterol influx mediated by acetylated low-density lipoprotein.
Conversely, lipid efflux in cholesterol-laden macrophages mediated by HDL(3) suppresses ABCG1 expression.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일: OSA00208W-100UL_ABCG1_P45844-1_Rabbit.svg, OSA00208W-100UL_ABCG1_P45844-1_Rabbit_PDP.jpeg)
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