Thermo Fisher Scientific ALS2CR2 Polyclonal Antibody
ALS2CR2 단백질을 인식하는 Thermo Fisher Scientific의 Goat Polyclonal 항체로, WB, IHC, ICC/IF에 사용 가능. 인간에 반응하며, 액상 형태로 0.5 mg/mL 농도. TBS buffer(pH 7.3, 0.5% BSA) 보존, -20°C에서 보관.
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Thermo Fisher Scientific ALS2CR2 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–3 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 3–5 µg/mL |
| Immunocytochemistry (ICC/IF) | 10 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide sequence (CDFPDEKDSYWEF) corresponding to the C-terminus amino acids of STRADB (aa 406–418) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_10984899 |
Product Specific Information
- Predicted to react with bovine and canine based on sequence homology.
- Tested in Peptide ELISA: antibody detection limit dilution 32,000.
Target Information
This gene encodes a protein belonging to the serine/threonine protein kinase STE20 subfamily. One of the active site residues in the protein kinase domain is altered, making it a pseudokinase.
The protein is part of a complex that activates serine/threonine kinase 11, which regulates cell polarity and energy metabolism. This complex controls the relocation of the kinase from the nucleus to the cytoplasm and is essential for G1 cell cycle arrest.
Additionally, the protein interacts with the X chromosome-linked inhibitor of apoptosis protein, enhancing anti-apoptotic activity via the JNK1 signal transduction pathway. Two pseudogenes are located on chromosomes 1 and 7.
Usage
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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