Thermo Fisher Scientific HCK Polyclonal Antibody
HCK 단백질에 특이적인 Rabbit Polyclonal Antibody로, Western Blot, ICC/IF, ELISA에 사용 가능. 인간 시료에 반응하며, 액상 형태로 1.4 mg/mL 농도. PBS 및 글리세롤 버퍼에 보관하며, 혈액세포 관련 연구에 적합.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 1–220 of human HCK (NP_001165600.1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.4 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2855217 |
Product Specific Information
Immunogen sequence:
MGCMKSKFLQ VGGNTFSKTE TSASPHCPVY VPDPTSTIKP GPNSHNSNTP GIREAGSEDI IVVALYDYEA IHHEDLSFQK GDQMVVLEES GEWWKARSLA TRKEGYIPSN YVARVDSLET EEWFFKGISR KDAERQLLAP GNMLGSFMIR DSETTKGSYS LSVRDYDPRQ GDTVKHYKIR TLDNGGFYIS PRSTFSTLQE LVDHYKKGND GLCQKLSVPC
Target Information
Hematopoietic cell kinase (HCK) is a SRC-related kinase expressed in lymphoid and hematopoietic cells and may play a role in certain forms of leukemia.
HCK (Alias: DKFZp686D0638) is a protein-tyrosine kinase predominantly expressed in hemopoietic cell types.
The encoded protein may help couple the Fc receptor to activation of the respiratory burst and may play a role in neutrophil migration and degranulation.
Alternate translation initiation site usage, including a non-AUG (CUG) codon, results in two isoforms with different subcellular localization.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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