Thermo Fisher Scientific PTGDR Polyclonal Antibody, MaxPab

Applications

Western Blot (WB)

• Tested Dilution: 1:500–1:1,000

Flow Cytometry (Flow)

• Tested Dilution: 1:500–1:1,000

Product Specifications

Product Specific Information

Protein sequence:

MKSPFYRCQN TTSVEKGNSA VMGGVLFSTG LLGNLLALGL LARSGLGWCS RRPLRPLPSV 
FYMLVCGLTV TDLLGKCLLS PVVLAAYAQN RSLRVLAPAL DNSLCQAFAF FMSFFGLSST 
LQLLAMALEC WLSLGHPFFY RRHITLRLGA LVAPVVSAFS LAFCALPFMG FGKFVQYCPG 
TWCFIQMVHE EGSLSVLGYS VLYSSLMALL VLATVLCNLG AMRNLYAMHR RLQRHPRSCT 
RDCAEPRADG REASPQPLEE LDHLLLLALM TVLFTMCSLP VIYRAYYGAF KDVKEKNRTS 
EEAEDLRALR FLSVISIVDP WIFIIFRSPV FRIFFHKIFI RPLRYRSRCS NSTNMESSL

Target Information

The protein encoded by this gene is a G-protein-coupled receptor that functions as a prostanoid DP receptor. Its activity is mediated by G-S proteins stimulating adenylate cyclase, leading to increased intracellular cAMP and Ca²⁺ levels. Knockout studies in mice suggest that prostaglandin D₂ (PGD₂), the ligand of this receptor, acts as a mast cell-derived mediator triggering asthmatic responses.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.