Thermo Fisher Scientific PTGDR Polyclonal Antibody, MaxPab
PTGDR 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체. Western blot 및 유세포분석에 사용 가능. 인간 시료 반응성, 비결합형 액상 항체로 친화 크로마토그래피 정제. 연구용으로만 사용.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
Flow Cytometry (Flow)
- Tested Dilution: 1:500–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | PTGDR (AAH40968, 1 a.a. – approximately 359 a.a.) full-length human protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Protein sequence:
MKSPFYRCQN TTSVEKGNSA VMGGVLFSTG LLGNLLALGL LARSGLGWCS RRPLRPLPSV
FYMLVCGLTV TDLLGKCLLS PVVLAAYAQN RSLRVLAPAL DNSLCQAFAF FMSFFGLSST
LQLLAMALEC WLSLGHPFFY RRHITLRLGA LVAPVVSAFS LAFCALPFMG FGKFVQYCPG
TWCFIQMVHE EGSLSVLGYS VLYSSLMALL VLATVLCNLG AMRNLYAMHR RLQRHPRSCT
RDCAEPRADG REASPQPLEE LDHLLLLALM TVLFTMCSLP VIYRAYYGAF KDVKEKNRTS
EEAEDLRALR FLSVISIVDP WIFIIFRSPV FRIFFHKIFI RPLRYRSRCS NSTNMESSLTarget Information
The protein encoded by this gene is a G-protein-coupled receptor that functions as a prostanoid DP receptor. Its activity is mediated by G-S proteins stimulating adenylate cyclase, leading to increased intracellular cAMP and Ca²⁺ levels. Knockout studies in mice suggest that prostaglandin D₂ (PGD₂), the ligand of this receptor, acts as a mast cell-derived mediator triggering asthmatic responses.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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