Thermo Fisher Scientific PTGDR Polyclonal Antibody, MaxPab

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

-

Flow Cytometry (Flow)

1:500-1:1,000

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG

Class

Polyclonal

Type

Antibody

Immunogen

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

See Label

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.4

Contains

no preservative

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

Sequence of this protein is as follows: MKSPFYRCQN TTSVEKGNSA VMGGVLFSTG LLGNLLALGL LARSGLGWCS RRPLRPLPSV FYMLVCGLTV TDLLGKCLLS PVVLAAYAQN RSLRVLAPAL DNSLCQAFAF FMSFFGLSST LQLLAMALEC WLSLGHPFFY RRHITLRLGA LVAPVVSAFS LAFCALPFMG FGKFVQYCPG TWCFIQMVHE EGSLSVLGYS VLYSSLMALL VLATVLCNLG AMRNLYAMHR RLQRHPRSCT RDCAEPRADG REASPQPLEE LDHLLLLALM TVLFTMCSLP VIYRAYYGAF KDVKEKNRTS EEAEDLRALR FLSVISIVDP WIFIIFRSPV FRIFFHKIFI RPLRYRSRCS NSTNMESSL

Target Information

The protein encoded by this gene is a G-protein-coupled receptor. It has been shown to function as a prostanoid DP receptor. The activity of this receptor is mainly mediated by G-S proteins that stimulate adenylate cyclase resulting in an elevation of intracellular cAMP and Ca2+. Knockout studies in mice suggest that the ligand of this receptor, prostaglandin D2 (PGD2), functions as a mast cell-derived mediator to trigger asthmatic responses.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.