Thermo Fisher Scientific GPS2 Monoclonal Antibody (3C4)

Applications

Tested Dilution

Publications

Western Blot (WB)

1-5 µg/mL

-

ELISA (ELISA)

0.3 ng/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG1, kappa

Class

Monoclonal

Type

Antibody

Clone

3C4

Immunogen

GPS2 (AAH13652, 228 a.a. approximately 327 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:GPS2,uniProtId:Q13227-1,ncbiNodeId:9606,antigenRange:228-327,antigenLength:327,antigenImageFileName:H00002874-M01_GPS2_Q13227-1_House_mouse.svg,antigenImageFileNamePDP:H00002874-M01_GPS2_Q13227-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

See Label

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.4

Contains

no preservative

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

Sequence of this protein is as follows: QPYAVHGHFQ PTQTGFLQPG GALSLQKQME HANQQTGFSD SSSLRPMHPQ ALHPAPGLLA SPQLPVQMQP AGKSGFAATS QPGPRLPFIQ HSQNPRFYHK

Target Information

This gene encodes a protein involved in G protein-mitogen-activated protein kinase (MAPK) signaling cascades. When overexpressed in mammalian cells, this gene could potently suppress a RAS- and MAPK-mediated signal and interfere with JNK activity, suggesting that the function of this gene may be signal repression. The encoded protein is an integral subunit of the NCOR1-HDAC3 (nuclear receptor corepressor 1-histone deacetylase 3) complex, and it was shown that the complex inhibits JNK activation through this subunit and thus could potentially provide an alternative mechanism for hormone-mediated antagonism of AP1 (activator protein 1) function.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.