Thermo Fisher Scientific GPS2 Monoclonal Antibody (3C4)
GPS2 단백질을 인식하는 Thermo Fisher Scientific의 Mouse Monoclonal Antibody (Clone 3C4). Western blot 및 ELISA에 적합하며, 인체 단백질 반응성을 가짐. Affinity chromatography로 정제된 액상 항체로, PBS buffer에 보존되어 있음.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–5 µg/mL |
| ELISA | 0.3 ng/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 3C4 |
| Immunogen | GPS2 (AAH13652, 228 a.a. ~ 327 a.a.) partial recombinant protein with GST tag (GST tag MW: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Protein sequence:
QPYAVHGHFQ PTQTGFLQPG GALSLQKQME HANQQTGFSD SSSLRPMHPQ ALHPAPGLLA SPQLPVQMQP AGKSGFAATS QPGPRLPFIQ HSQNPRFYHK
Target Information
This gene encodes a protein involved in G protein–mitogen-activated protein kinase (MAPK) signaling cascades. Overexpression in mammalian cells suppresses RAS- and MAPK-mediated signaling and interferes with JNK activity, suggesting a role in signal repression. The encoded protein is an integral subunit of the NCOR1–HDAC3 (nuclear receptor corepressor 1–histone deacetylase 3) complex, which inhibits JNK activation and may contribute to hormone-mediated antagonism of AP1 (activator protein 1) function.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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