Thermo Fisher Scientific CRTAC1 Polyclonal Antibody
Human CRTAC1 단백질을 인식하는 Rabbit Polyclonal Antibody로, Western blot과 IHC(P)에서 검증됨. 항원 친화 크로마토그래피로 정제되었으며, PBS 기반 버퍼에 보존. 세포외기질 단백질 표지 연구용으로 적합.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL | - |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:20–1:50 | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human CRTAC1. Recombinant protein control fragment (Product # RP-89891) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2640174 |
Product Specific Information
Immunogen sequence:
VVTDFDGDGM LDLILSHGES MAQPLSVFRG NQGFNNNWLR VVPRTRFGAF ARGAKVVLYT KKSGAHLRII DGGSGYLCEM EPVAHFGLGK DEASSVEVTW PDGKMVSRNV ASGEMNSVLE ILYPRDEDTL QDPAP
Highest antigen sequence identity to the following orthologs:
- Mouse: 94%
- Rat: 93%
Target Information
CRTAC1 encodes a glycosylated extracellular matrix protein found in the interterritorial matrix of articular deep zone cartilage.
This protein serves as a marker to distinguish chondrocytes from osteoblasts and mesenchymal stem cells in culture.
The presence of FG-GAP motifs and an RGD integrin-binding motif suggests involvement in cell-cell or cell-matrix interactions.
Copy number alterations in this gene have been observed in neurofibromatosis type 1-associated glomus tumors.
Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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