Thermo Fisher Scientific ERI1 Polyclonal Antibody
ERI1 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot에 적합합니다. 인간 ERI1 내부 서열에서 유래한 합성 펩타이드로 면역화되었습니다. 비결합형 액상 형태이며, 1 mg/mL 농도로 제공됩니다. 연구용으로만 사용 가능합니다.
- 카탈로그번호
- PA539605
- 판매단위
- pk
카탈로그
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide derived from the internal region of human ERI1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2556157 |
Target Information
RNA exonuclease that binds to the 3′-end of histone mRNAs and degrades them, suggesting an essential role in histone mRNA decay after replication. Efficient degradation requires 2′ and 3′-hydroxyl groups at the last nucleotide of the histone 3′-end. Also degrades 3′-overhangs of short interfering RNAs (siRNAs) in vitro, implying a role in RNA interference (RNAi) regulation. Requires binding to the 5′-ACCCA-3′ sequence in the stem-loop structure and can bind other mRNAs. It is necessary for 5.8S rRNA 3′-end processing and binds with high affinity to the stem-loop structure of replication-dependent histone pre-mRNAs.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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