Thermo Fisher Scientific ZHX2 Monoclonal Antibody (5E2)
ZHX2 단백질을 인식하는 Mouse IgG2b 단클론 항체로 Western blot과 ELISA에 적합. 인간 시료 반응성. 액상 형태이며 방부제 미포함. -20°C에서 보관하며 연구용으로 사용.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
ELISA
- Tested Dilution: 1:500–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 5E2 |
| Immunogen | ZHX2 (NP_055758, 691–788 a.a) partial recombinant protein with GST tag (MW of GST tag: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Storage Buffer | Ascites |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein:
MEQYQHQPMA DDHGYDAVAR KATKPMAESP KNGGDVVPQY YKDPKKLCEE DLEKLVTRVK VGSEPAKDCL PAKPSEATSD RSEGSSRDGQ GSDENEESTarget Information
Zinc-fingers and homeobox (ZHX) proteins are transcription factors that interact with the activation domain of the A subunit of nuclear factor-Y (NF-YA).
ZHX1–3 are ubiquitously expressed in various tissues and act as transcriptional repressors localized in the nucleus.
They contain two Cys(2)-His(2)-type zinc-finger motifs and five homeodomains (HDs), enabling homodimer and heterodimer formation.
Dimerization is not required for repressor activity.
Hypermethylation-mediated silencing of ZHX2 is an epigenetic event involved in hepatocellular carcinoma (HCC).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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