Thermo Fisher Scientific PFKFB1 Polyclonal Antibody
PFKFB1 단백질에 특이적인 Rabbit Polyclonal Antibody로, Western blot, IHC, ICC 등 다양한 응용에 사용 가능. Human, Mouse, Rat 반응성. Protein A 정제, 1 mg/mL 농도, -20°C 보관. 연구용으로만 사용.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:100–1:500 |
| Immunohistochemistry (Frozen) (IHC-F) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH-conjugated synthetic peptide derived from human PFKFB1 (amino acids 21–120) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, typically the γ-phosphate of ATP, onto an acceptor amino acid in a substrate protein. Through this mechanism, protein kinases mediate most signal transduction in eukaryotic cells, regulating metabolism, transcription, cell cycle progression, cytoskeletal rearrangement, cell movement, apoptosis, and differentiation.
The protein kinase family, with more than 500 gene products, is one of the largest in eukaryotes. It is classified into eight major groups based on sequence comparisons of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The AGC kinase group includes 63 kinases such as:
- Cyclic nucleotide-regulated protein kinases (PKA & PKG)
- Diacylglycerol-activated/phospholipid-dependent protein kinase C (PKC)
- RAC/Akt protein kinases
- G protein-coupled receptor kinases (ARK)
- Ribosomal protein S6 kinases (RSK)
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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