
Thermo Fisher Scientific p115 Polyclonal Antibody
Rabbit 유래의 p115 단백질에 대한 Polyclonal Antibody로, Western blot, IHC, IP 등 다양한 응용에 사용 가능. 인간 Vesicle Docking Protein p115의 912-962 잔기 구간을 면역원으로 제작. 액상 형태로 4°C 보관, 1 mg/mL 농도.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 – 1:10,000 |
| Immunohistochemistry (IHC) | 1:500 – 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:500 – 1:2,000 |
| Immunoprecipitation (IP) | 2–10 µg/mg lysate |
Product Specifications
| Specification | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 912 to 962 of human Vesicle Docking Protein p115 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- Application Note: For IHC, epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
Target Information
The protein encoded by this gene is a peripheral membrane protein that cycles between the cytosol and the Golgi apparatus during interphase. It is regulated by phosphorylation: the dephosphorylated protein associates with the Golgi membrane and dissociates upon phosphorylation. Ras-associated protein 1 recruits this protein to COPII vesicles during budding from the endoplasmic reticulum, where it interacts with COPII vesicle-associated SNAREs to form a cis-SNARE complex promoting targeting to the Golgi apparatus. Transport from the ER to the cis/medial Golgi compartments requires the coordinated action of this gene product, GM130, and giantin.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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