Thermo Fisher Scientific STK11 Monoclonal Antibody (OTI10A3), TrueMAB
STK11 단백질을 표적으로 하는 Mouse IgG1 단클론 항체로, Western blot 및 IHC(P) 실험에 적합. Human 시료 반응성, 고순도 Affinity chromatography 정제, 안정적인 PBS/BSA/glycerol 저장 buffer 구성. 연구용으로만 사용 가능.
- 판매단위
- pk
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:150
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI10A3 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 1-236 of human STK11 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
LKB1 (also known as STK11 - Serine/threonine-protein kinase STK11), a member of the serine/threonine kinase family, is a tumor suppressor.
LKB1 physically associates with p53 and regulates specific p53-dependent apoptosis pathways.
It is present in both the cytoplasm and nucleus and translocates to mitochondria during apoptosis.
LKB1 functions as a master upstream protein kinase, regulating AMPK-related kinases as well as AMPK.
Mutations in the LKB1 gene are associated with Peutz-Jeghers syndrome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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