Thermo Fisher Scientific ISCU Polyclonal Antibody
Thermo Fisher Scientific의 ISCU Polyclonal Antibody는 인간 ISCU 단백질을 인식하는 Rabbit IgG 항체입니다. Western blot 및 IHC(P)에서 검증되었으며, 고순도 항원 친화 크로마토그래피로 정제되었습니다. 연구용으로 사용되며, 안정적인 액상 형태로 제공됩니다.
- 카탈로그번호
- PA563455
- 판매단위
- pk
카탈로그
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Applications
- Western Blot (WB): 0.04–0.4 µg/mL
- Immunohistochemistry (Paraffin) (IHC (P)): 1:200–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human ISCU. Recombinant protein control fragment (Product #RP-103303) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2642789 |
Product Specific Information
Immunogen sequence:
PARLYHKKVV DHYENPRNVG SLDKTSKNVG TGLVGAPACG DVMKLQIQVD EKGKIVDARF K
Ortholog sequence identity:
- Mouse: 100%
- Rat: 100%
Target Information
Iron-sulfur (Fe-S) clusters are essential cofactors for numerous mitochondrial and cellular enzymes. They consist of sulfur and iron and are synthesized through a multi-step process involving cysteine desulfurases, iron donors, chaperones, and scaffold proteins.
The ISCU gene encodes two isomeric forms, ISCU1 and ISCU2, which serve as Fe-S cluster scaffold proteins. Mutations in ISCU are associated with myopathy characterized by severe exercise intolerance and myoglobinuria.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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