Thermo Fisher Scientific LFG Polyclonal Antibody
다양한 종에서 반응하는 Rabbit Polyclonal LFG 항체로 Western blot, IHC, Flow cytometry에 사용 가능. Lifeguard 단백질(1-50aa) 기반 합성 펩타이드로 제작. 단백질 G 정제, 1 mg/mL 농도, PBS 버퍼 및 sodium azide 함유. 신경세포 사멸 억제 연구에 적합.
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Thermo Fisher Scientific LFG Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–3 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 10 µg/mL |
| Flow Cytometry (Flow) | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Dog, Human, Mouse, Non-human primate, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to residues 1–50 of human Lifeguard |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.0 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2278102 |
Target Information
LFG (Lifeguard) is a seven-transmembrane protein that inhibits apoptotic cell death induced by the Fas receptor. It is a human homolog of rat NMP35 and contains a conserved transmembrane domain and a small cytoplasmic domain. LFG protects cells from Fas-mediated neuronal cell death without affecting Fas expression or FADD binding. It does not protect against TNF-alpha mediated cell death. LFG is ubiquitously expressed, with higher expression in the hippocampus and other neural tissues, suggesting a protective role in neurodegenerative diseases.
Usage Note
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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