ELK Biotechnology COX-2 (2G1) Mouse mAb
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카탈로그 번호 | 설명 | 상태 | 단위 | 가격 | 가격(VAT포함) | 수량 / 장바구니 / 찜 |
EM1339 | ELK Biotechnology EM1339 COX-2 (2G1) Mouse mAb, 50UL pk | 재고문의 | pk | 320,000원 | 352,000원 |
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Product name: | COX-2 (2G1) Mouse mAb |
Reactivity: | Human, Mouse, Rat |
Alternative Names: | PTGS2 antibody, Prostaglandin H2 synthase 2 antibody, PGHS 2 antibody, Glucocorticoid-regulated inflammatory cyclooxygenase antibody |
Source: | Mouse |
Applications: | IHC |
Species: | Human |
Recommended dilutions: | IHC 1:100-200 |
Immunogen: | Synthetic Peptide |
Storage: | PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles. |
Clonality: | Monoclonal |
Isotype: | IgG1 |
Concentration: | 1mg/ml |
Observed band: | 70kDa |
GeneID(Human): | 5743 |
Human Swiss-Prot No: | P35354 |
Cellular localization: | Endoplasmic reticulum, Membrane, Microsome |
Background: | Prostaglandin-endoperoxide synthase 2, also known as cyclooxygenase-2 or simply COX-2, is an enzyme that in humans is encoded by the PTGS2 gene. There are two isozymes of COX encoded by distinct gene products: a constitutive COX-1 (this enzyme) and an inducible COX-2, which differ in their regulation of expression and tissue distribution. The expression of these two transcripts is differentially regulated by relevant cytokines and growth factors. A splice variant of COX-1 termed COX-3 was identified in the CNS of dogs, but does not result in a functional protein in humans. Two smaller COX-1-derived proteins (the partial COX-1 proteins PCOX-1A and PCOX-1B) have also been discovered, but their precise roles are yet to be described. |
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