ELK Biotechnology ATG5 (3C7) Mouse mAb
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| Product name: | ATG5 (3C7) Mouse mAb |
| Reactivity: | Human, Mouse, Rat |
| Alternative Names: | APG5, APG5L, ASP, Autophagy protein 5 antibody |
| Source: | Mouse |
| Applications: | WB, IHC |
| Species: | Human |
| Recommended dilutions: | WB 1:5,000-10,000 IHC 1:100-200 |
| Immunogen: | Recombinant Protein |
| Storage: | PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles. |
| Clonality: | Monoclonal |
| Isotype: | IgG1 |
| Concentration: | 1mg/ml |
| Observed band: | 55kDa |
| GeneID（Human）: | 9494 |
| Human Swiss-Prot No: | Q9H1Y0 |
| Cellular localization: | Cytoplasm, Membrane |
| Background: | Autophagy is generally activated by conditions of nutrient deprivation but has also been associated with a number of physiological processes including development, differentiation, neurodegeneration, infection, and cancer. Formation of the autophagosome involves a ubiquitin-like conjugation system in which Atg12 is covalently bound to Atg5 and targeted to autophagosome vesicles. This conjugation reaction is mediated by the ubiquitin E1-like enzyme Atg7 and the E2-like enzyme Atg10. |
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