ELK Biotechnology WNK4 rabbit pAb
WNK4 rabbit pAb는 인간, 랫, 마우스에 반응하는 폴리클로날 항체로, WB 및 ELISA에 사용됩니다. 세포 간 접합부 단백질 WNK4를 인식하며, NaCl 재흡수와 K⁺ 분비 조절 연구에 적합합니다. -20°C에서 1년 보관 가능합니다.
- 카탈로그번호
- ES10220-xxxxx (2개 옵션)
- 판매단위
- pk
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2개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다ELK Biotechnology · ELK Biotechnology WNK4 rabbit pAb
제품명
WNK4 rabbit pAb
적용 분야
- WB (Western Blot)
- ELISA
권장 희석 배수
- WB: 1:500–1:2000
- ELISA: 1:5000–1:20000
제품 정보
| 항목 | 내용 |
|---|---|
| Immunogen | Synthesized peptide derived from part region of human protein |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 136 kD |
| Gene ID (Human) | 65266 |
| Human Swiss-Prot No. | Q96J92 |
| Species Reactivity | Human, Rat, Mouse |
세포 내 위치
Cell junction, tight junction. Present exclusively in intercellular junctions in the distal convoluted tubule and in both the cytoplasm and intercellular junctions in the cortical collecting duct. WNK4 is part of the tight junction complex.
배경 정보
This gene encodes a member of the WNK family of serine-threonine protein kinases. The kinase is part of the tight junction complex in kidney cells, and regulates the balance between NaCl reabsorption and K(+) secretion. The kinase regulates the activities of several types of ion channels, cotransporters, and exchangers involved in electrolyte flux in epithelial cells. Mutations in this gene result in pseudohypoaldosteronism type IIB. [provided by RefSeq, Sep 2009]
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