Thermo Fisher Scientific Alivin 1 Polyclonal Antibody
Rabbit polyclonal antibody recognizing Alivin 1 protein. Validated for Western blot at 1:500 dilution. Targets residues 449–464 of mouse and rat Alivin 1. Suitable for neuronal survival research. For research use only.
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Applications
- Western Blot (WB): 1:500 dilution
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide mapping to residues 449–464 of mouse and rat Alivin 1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2226573 |
Product Specific Information
This antibody has 81% sequence homology with human.
Target Information
Alivin 1 (ali1) is a novel primary response gene that is activity-dependent and promotes the survival of neurons. Sequence analyses show that rat, mouse, and human Ali1 proteins contain seven leucine-rich repeats, one IgC2-like loop, and a transmembrane domain, displaying homology to Kek and Trk families. Expression of ali1 promotes depolarization-dependent survival of granule neurons. Mouse ali1 is mapped to chromosome 15, approximately 55.3 cM from the centromere, syntenic to loci associated with familial Alzheimer’s disease type 5 and Parkinson’s disease 8 on human chromosome 12.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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