Thermo Fisher Scientific GSR Monoclonal Antibody (6B4)
Thermo Fisher Scientific의 GSR Monoclonal Antibody (6B4)는 인간 GSR 단백질을 인식하는 Mouse IgG2a 항체입니다. Western blot, IHC, ELISA에 적합하며, 높은 특이성과 안정성을 제공합니다. 연구용으로만 사용되며 항산화 관련 단백질 분석에 유용합니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–5 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 6 µg/mL |
| ELISA | 0.03 ng/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 6B4 |
| Immunogen | GSR (NP_000628, 413–522 a.a.) partial recombinant protein with GST tag (MW of GST tag: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
TVVFSHPPIG TVGLTEDEAI HKYGIENVKT YSTSFTPMYH AVTKRKTKCV MKMVCANKEE KVVGIHMQGL GCDEMLQGFA VAVKMGATKA DFDNTVAIHP TSSEELVTLR
Target Information
This gene encodes a member of the class-I pyridine nucleotide-disulfide oxidoreductase family.
This enzyme is a homodimeric flavoprotein and a central component of cellular antioxidant defense.
It reduces oxidized glutathione disulfide (GSSG) to the sulfhydryl form GSH, an important cellular antioxidant.
Rare mutations in this gene cause hereditary glutathione reductase deficiency.
Multiple alternatively spliced transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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