Thermo Fisher Scientific SP100 Polyclonal Antibody, MaxPab

Thermo Fisher Scientific SP100 Polyclonal Antibody, MaxPab

Applications

• Western Blot (WB): Tested dilution 1:1,000

Product Specifications

Product Specific Information

Sequence of this protein is as follows:
MAGGGGDLST RRLNECISPV ANEMNHLPAH SHDLQRMFTE DQGVDDRLLY DIVFKHFKRN KVEISNAIKK TFPFLEGLRD RDLITNKMFE DSQDSCRNLV PVQRVVYNVL SELEKTFNLP VLEALFSDVN MQEYPDLIHI YKGFENVIHD KLPLQESEEE EREERSGLQL SLEQGTGENS FRSLTWPPSG SPSHAGTTPP ENGLSEHPCE TEQINAKRKD TTSDKDDSLG SQQTNEQCAQ KAEPTESCEQ IAVQVNNGDA GREMPCPLPC DEESPEAELH NHGIQINSCS VRLVDIKKEK PFSNSKVECQ AQARTHHNQA SDIIVISSED SEGSTDVDEP LEVFISAPRS EPVINNDNPL ESNDEKEGQE ATCSRPQIVP EPMDFRKLST FRESFKKRVI GQDHDFSESS EEEAPAEASS GALRSKHGEK APMTSRSTST WRIPSRKRRF SSSDFSDLSN GEELQETCSS SLRRGSGKED

Target Information

This gene encodes a subnuclear organelle and major component of the PML (promyelocytic leukemia)-SP100 nuclear bodies.
PML and SP100 are covalently modified by the SUMO-1 modifier, which is crucial for nuclear body interactions.
The encoded protein binds heterochromatin proteins and is thought to play roles in tumorigenesis, immunity, and gene regulation.
Alternatively spliced variants have been identified for this gene, one of which encodes a high-mobility group protein.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.