Thermo Fisher Scientific Ubinuclein 1/2 Polyclonal Antibody
Ubinuclein 1/2 단백질을 인식하는 Thermo Fisher Scientific의 염소 폴리클로날 항체. Western blot에 최적화되어 있으며, 인간 반응성과 다양한 종에 예측 반응. 액상 형태, 0.5 mg/mL 농도, -20°C 보관.
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Applications
Western Blot (WB)
- Tested Dilution: 1–3 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide with sequence C-DNSEAYDELVPASLT, from the internal region of UBN1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2554548 |
Product Specific Information
- This antibody is predicted to react with mouse, rat, dog, pig, cow, and zebrafish based on sequence homology.
- Tested in Peptide ELISA: antibody detection limit dilution 1:128,000.
Target Information
Ubinuclein 1 (UBN1) is a ubiquitously expressed, evolutionarily conserved protein that binds to proliferation-promoting genes repressed by senescence-associated heterochromatin foci (SAHF).
UBN1 associates with various transcription factors and histone methyltransferase activity, is indispensable for SAHF formation, and acts as a regulator of senescence.
Although ubinuclein is mainly localized to the nucleus, in cells forming tight junctions it is recruited to cell adhesion complexes depending on cell density.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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