Thermo Fisher Scientific Melanopsin Polyclonal Antibody
Rabbit polyclonal antibody targeting human melanopsin for WB and IHC applications. Recognizes melanopsin involved in circadian rhythm regulation. Lyophilized form, unconjugated, reconstitute in sterile water. Suitable for research use only, not f...
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:300–1:2,000 |
| Immunohistochemistry (IHC) | 1:300–1:2,000 |
| Miscellaneous (PubMed) | - |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / Ig |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide from aa region 420–470 of human melanopsin conjugated to an immunogenic carrier protein |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not Determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term; for long-term storage, store at -20°C avoiding freeze/thaw cycles. Glycerol (1:1) may be added for stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Reconstitute in 100 µL of sterile water.
- Centrifuge to remove any insoluble material.
- Specificity: Melanopsin.
Target Information
Melanopsin is an opsin-like protein found in the retinal ganglion cells of mammals. It is part of a secondary optical system that parallels the classic rod and cone system. This system reports directly to the suprachiasmatic nucleus and regulates circadian rhythms. Melanopsin is considered the primary photopigment responsible for circadian rhythm regulation. Knockout mice lacking melanopsin show reduced ability to entrain to light and dark cycles.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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