Thermo Fisher Scientific SYT10 Polyclonal Antibody
SYT10 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot 및 IHC(P)에서 사용 가능. 인간, 생쥐, 랫트 반응성. 고순도 친화 크로마토그래피 정제. 연구용으로만 사용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000–1:3,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthesized peptide derived from human SYT10 (amino acids 430–452, UniProt ID: Q6XYQ8-1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2691983 |
Product Specific Information
Predicted to react with Human, Mouse, and Rat samples.
Target Information
SYT10 is a Ca²⁺ sensor specifically required for the Ca²⁺-dependent exocytosis of secretory vesicles containing IGF1 in neurons of the olfactory bulb. Exocytosis of IGF1 is required for sensory perception of smell.
SYT10 is not involved in Ca²⁺-dependent synaptic vesicle exocytosis. It acts through Ca²⁺ and phospholipid binding to the C2 domain: Ca²⁺ induces binding of the C2-domains to phospholipid membranes and to assembled SNARE complexes; both actions contribute to triggering exocytosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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