Thermo Fisher Scientific PSD-95 Polyclonal Antibody
PSD-95 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot, IHC, ICC 등 다양한 응용 가능. Mouse와 Rat에 반응하며, 높은 특이성과 재현성을 제공. 장기 보관 시 -20°C에서 안정적으로 유지.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:3,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:1,000 |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100–1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:100–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein encompassing a sequence within the N-terminus region of Mouse PSD95 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.15 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7, with 20% glycerol, 1% BSA |
| Contains | 0.025% ProClin 300 |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2792906 |
Product Specific Information
- Keep as concentrated solution.
- Predicted reactivity: Human (99%), Mouse (100%), Rat (99%), Rhesus Monkey (99%), Bovine (99%).
- Positive Control: Mouse brain, Rat brain.
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Post Synaptic Density 95 kDa (PSD-95), also known as synapse associated protein 90 kDa (SAP90), is a membrane-associated protein found in the postsynaptic density of forebrain neurons and certain presynaptic structures in the cerebellum.
PSD-95 contains three PDZ domains, an SH3 domain, and a Guanylate Kinase (GuK) domain. It participates in clustering NMDA receptors and Shaker-type potassium channels at synaptic membranes in CNS neurons.
Interactions occur via C-terminal sequence motifs (T/SXV) or PDZ-PDZ domain associations, involving other neuronal proteins such as beta-1 adrenergic receptors, serotonin receptors, sodium channel subunits, and neuronal nitric oxide synthase (nNOS).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
- PA5-85769_PSD-95_Q62108-1_Rabbit.svg
- PA5-85769_PSD-95_Q62108-1_Rabbit_PDP.jpeg
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