Thermo Fisher Scientific TNRC6C Monoclonal Antibody (3C4)

Applications

Tested Dilution

Publications

Western Blot (WB)

1-5 µg/mL

-

ELISA (ELISA)

10 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG2a, kappa

Class

Monoclonal

Type

Antibody

Clone

3C4

Immunogen

TNRC6C (NP_061869.2, 1 a.a. approximately 100 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:TNRC6C,uniProtId:Q9HCJ0-1,ncbiNodeId:9606,antigenRange:1-100,antigenLength:1690,antigenImageFileName:H00057690-M14_TNRC6C_Q9HCJ0-1_House_mouse.svg,antigenImageFileNamePDP:H00057690-M14_TNRC6C_Q9HCJ0-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

See Label

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.4

Contains

no preservative

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

Sequence of this protein is as follows: MATGSAQGNF TGHTKKTNGN NGTNGALVQS PSNQSALGAG GANSNGSAAR VWGVATGSSS GLAHCSVSGG DGKMDTMIGD GRSQNCWGAS NSNAGINLNL

Target Information

Plays a role in RNA-mediated gene silencing by micro-RNAs (miRNAs). Required for miRNA-dependent translational repression of complementary mRNAs by argonaute family proteins. As scaffoldng protein associates with argonaute proteins bound to partially complementary mRNAs and simultaneously can recruit CCR4-NOT and PAN deadenylase complexes.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.