Thermo Fisher Scientific PDK1 Monoclonal Antibody (3B7)
Human PDK1 단백질을 인식하는 Mouse monoclonal antibody (Clone 3B7). ELISA에 적합하며, 세포 내 신호전달 및 저산소 반응 연구에 활용 가능. 액상 형태, PBS buffer, 보존제 없음, -20°C 보관.
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Applications
- ELISA (ELISA): Tested dilution 30 ng/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 3B7 |
| Immunogen | PDK1 (AAH39158, 203–302 a.a) partial recombinant protein with GST tag (MW of GST tag: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
GGKGKGSPSH RKHIGSINPN CNVLEVIKDG YENARRLCDL YYINSPELEL EELNAKSPGQ PIQVVYVPSH LYHMVFELFK NAMRATMEHH ANRGVYPPIQ
Target Information
PDK1 (3-phosphoinositide dependent kinase-1) is a serine/threonine protein kinase localized to the plasma membrane.
It plays a vital role in insulin-induced glycogen synthesis, PKC activation, and activation of the AGC subfamily of protein kinases.
PDK1 is essential for cellular responses to hypoxia and contributes to cell proliferation under hypoxic conditions.
It protects cells against apoptosis induced by hypoxia and oxidative stress.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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