Thermo Fisher Scientific HK2 Polyclonal Antibody
Thermo Fisher Scientific HK2 Polyclonal Antibody는 인간 HK2 단백질을 인식하는 토끼 유래 IgG 폴리클로날 항체입니다. Western blot과 IHC(P)에서 검증되었으며, 항원 친화 크로마토그래피로 정제되었습니다. 연구용으로만 사용되며, 인슐린 반응성 조직의 HK2 분석에 적합합니다.
- 카탈로그번호
- PA583021
- 판매단위
- pk
카탈로그
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Thermo Fisher Scientific HK2 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human HK2. Recombinant protein control fragment (Product #RP-95130) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2790177 |
Product Specific Information
Immunogen sequence:
GKLSPELLNT GRFETKDISD IEGEKDGIRK AREVLMRLGL DPTQEDCVAT HRICQIVSTR SA
Target Information
In vertebrates, there are four major glucose-phosphorylating isoenzymes: hexokinase I, II, III, and IV. Hexokinase activity catalyzes the first step in several metabolic pathways, phosphorylating glucose to produce glucose-6-phosphate, thus committing glucose to the glycolytic pathway. Hexokinase is an allosteric enzyme inhibited by its product GLC-6-P.
Hexokinase 2 (HK2) is predominantly expressed in insulin-responsive tissues such as skeletal muscle. Expression of this gene is insulin-responsive, and studies in rat suggest that it is involved in the increased glycolysis rate observed in rapidly growing cancer cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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