Thermo Fisher Scientific MPP2 Polyclonal Antibody, MaxPab

Applications

• Western Blot (WB): 1:500–1:1,000

Product Specifications

Product Specific Information

Sequence of this protein is as follows:

MPVAATNSET AMQQVLDNLG SLPSATGAAE LDLIFLRGIM ESPIVRSLAK AHERLEETKL EAVRDNNLEL VQEILRDLAQ LAEQSSTAAE LAHILQEPHF QSLLETHDSV ASKTYETPPP SPGLDPTFSN QPVPPDAVRM VGIRKTAGEH LGVTFRVEGG ELVIARILHG GMVAQQGLLH VGDIIKEVNG QPVGSDPRAL QELLRNASGS VILKILPSYQ EPHLPRQVFV KCHFDYDPAR DSLIPCKEAG LRFNAGDLLQ IVNQDDANWW QACHVEGGSA GLIPSQLLEE KRKAFVKRDL ELTPNSGTLC GSLSGKKKKR MMYLTTKNAE FDRHELLIYE EVARMPPFRR KTLVLIGAQG VGRRSLKNKL IMWDPDRYGT TVPYTSRRPK DSEREGQGYS FVSRGEMEAD VRAGRYLEHG EYEGNLYGTR IDSIRGVVAA GKVCVLDVNP QAVKVLRTAE FVPYVVFIEA PDFETLRAMN RAALESGIST KQLTEADLRR TVEESSRIQR GYGHYFDLCL VNSNLERTFR ELQTAMEKLR TEPQWVPVSW VY

Target Information

The MAGUK (membrane-associated guanylate kinase homologs) family of proteins contain multiple protein-binding domains and are involved in cell junction organization, tumor suppression, and signaling. The MAGUK family is divided into four subfamilies: DLG-like, ZO1-like, p55-like, and LIN2-like.
MPP2 (membrane protein, palmitoylated 2), also known as MAGUK p55 subfamily member 2, discs large homolog 2 or DLG2, is a 576 amino acid protein belonging to the MAGUK family that exists as three alternatively spliced isoforms.
MPP2 contains one guanylate kinase-like domain, a PDZ (DHR) domain, two L27 domains, and a single SH3 domain. The gene encoding MPP2 maps to the same segment of human chromosome 17 as MPP3, with which MPP2 likely shares similar function and structural organization.

For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.