Thermo Fisher Scientific JARID1A/RBP2 Polyclonal Antibody
JARID1A/RBP2 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot 및 Immunoprecipitation에 적합. 액상 형태, 4°C 보관, 1년 권장 보관 기간. 연구용으로만 사용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000–1:10,000
Immunoprecipitation (IP)
- Tested Dilution: 2–10 µg/mg lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 1640 and 1690 of human Jumonji/ARID Domain-Containing Protein 1A / Retinoblastoma Binding Protein 2 Homolog 1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.20 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt.
Target Information
UPF3B is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. The protein is one of two functional homologs to yeast Upf3p. It binds to mRNA and remains bound after nuclear export, acting as a nucleocytoplasmic shuttling protein. Together with Y14, it forms a complex that binds specifically 20 nt upstream of exon-exon junctions.
This gene encodes a protein that participates in nonsense-mediated mRNA decay (NMD), which degrades mRNAs containing premature stop codons. Located on the long arm of chromosome X, two splice variants encoding different isoforms have been identified.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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