Thermo Fisher Scientific SLC7A5 Polyclonal Antibody
SLC7A5 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체로, IHC(P)에서 검증됨. 인간, 개, 영장류에 반응하며 항원 친화 크로마토그래피로 정제됨. 세포 내 아미노산 수송 연구에 적합.
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Applications and Tested Dilution
- Immunohistochemistry (Paraffin) [IHC (P)]: 7 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Dog, Human, Non-human primate |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic 15 amino acid peptide from internal region of human SLC7A5 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.6 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS |
| Contains | 0.1% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2551568 |
Product Specific Information
Percent identity with other species by BLAST analysis:
- Monkey, Marmoset, Dog (100%)
- Human, Panda, Bat, Rabbit (93%)
- Elephant, Bovine, Horse (87%)
Target Information
Solute carrier family 7 member 5 (SLC7A5), also known as large neutral amino acids transporter small subunit 1, is a sodium-independent, high-affinity transporter of large neutral amino acids such as phenylalanine, tyrosine, leucine, arginine, and tryptophan, when associated with SLC3A2/4F2hc.
It is involved in cellular amino acid uptake and transport of L-DOPA across the blood-brain barrier, as well as thyroid hormones (T3, T4) across cell membranes in tissues such as the placenta.
Acts as an amino acid exchanger and plays a role in neuronal cell proliferation (neurogenesis) in the brain.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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