Thermo Fisher Scientific Human MAP4K2 (GCK), His Tag Recombinant Protein
인간 MAP4K2(GCK) 단백질을 곤충 세포에서 발현한 His-tag 재조합 단백질. JNK 경로 활성화 연구에 적합하며, 고순도 정제된 액상 형태로 제공. -80°C에서 안정적으로 보관 가능하며, 연구용으로만 사용.
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Thermo Fisher Scientific Human MAP4K2 (GCK), His Tag Recombinant Protein
Applications
- Kinase Assay (KA): Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species | Human |
| Expression System | Insect cells |
| Amino Acid Sequence | Full length |
| Tag | His-tag |
| Molecular Weight | 95.6 kDa |
| Class | Recombinant |
| Type | Protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Purified |
| Storage Buffer | 50 mM Tris (pH 7.5), 0.02% Triton X-100, 50% glycerol, 2 mM DTT, 0.5 mM EDTA, 150 mM NaCl |
| Contains | No preservative |
| Storage Conditions | -80°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Dry ice |
Product Specific Information
- For maximum recovery, please spin prior to use.
- Aliquots of 5 µg, 10 µg, and 20 µg sizes are not recommended; use material directly from original packaging until exhausted.
- For larger sizes, reduce freeze/thaw cycles by preparing aliquots (not below 20 µL).
- Do not store kinase in diluted form.
- Properly stored at -80°C, product is guaranteed for 6 months from date of purchase.
- Protein Form: Full Length
Target Information
MAP4K2 (GCK) is a serine/threonine protein kinase that activates the JNK pathway. It is expressed in many tissues but restricted to germinal center cells in lymphoid follicles, where it may participate in B-cell differentiation.
This kinase may also regulate vesicle targeting or fusion. It can be activated by TNF-alpha and specifically activates MAP kinases. MAP4K2 interacts with TNF receptor-associated factor 2 (TRAF2), which is involved in the activation of MAP3K1/MEKK1.
Usage Restriction
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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