Thermo Fisher Scientific Human MAP4K2 (GCK), His Tag Recombinant Protein

Thermo Fisher Scientific Human MAP4K2 (GCK), His Tag Recombinant Protein

Applications

• Kinase Assay (KA): Assay-dependent

Product Specifications

Product Specific Information

• For maximum recovery, please spin prior to use.
• Aliquots of 5 µg, 10 µg, and 20 µg sizes are not recommended; use material directly from original packaging until exhausted.
• For larger sizes, reduce freeze/thaw cycles by preparing aliquots (not below 20 µL).
• Do not store kinase in diluted form.
• Properly stored at -80°C, product is guaranteed for 6 months from date of purchase.
• Protein Form: Full Length

Target Information

MAP4K2 (GCK) is a serine/threonine protein kinase that activates the JNK pathway. It is expressed in many tissues but restricted to germinal center cells in lymphoid follicles, where it may participate in B-cell differentiation.
This kinase may also regulate vesicle targeting or fusion. It can be activated by TNF-alpha and specifically activates MAP kinases. MAP4K2 interacts with TNF receptor-associated factor 2 (TRAF2), which is involved in the activation of MAP3K1/MEKK1.

Usage Restriction

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.