Thermo Fisher Scientific SPDYA Polyclonal Antibody
SPDYA 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체로, Western blot에 최적화되어 있습니다. 인간, 마우스, 랫트 반응성이 있으며, 항원 친화 크로마토그래피로 정제되었습니다. 세포 주기 조절 연구에 적합합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant full length Human SPDYA (UniProt ID: Q5MJ70-2, antigen length: 313 aa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2719807 |
Product Specific Information
This antibody was affinity-purified from rabbit antiserum using an epitope-specific immunogen. Purity is >95% as confirmed by SDS-PAGE.
Target Information
Speedy A (SPDYA), also known as SPDY1, Ringo3, or SPY1, is a 313 amino acid nuclear protein belonging to the speedy/ringo family.
It is highly expressed in testis and at lower levels in brain, kidney, heart, bone marrow, colon, lung, liver, spleen, and placenta.
Speedy A regulates the G1/S phase transition of the cell cycle by binding and activating Cdc2 p34, Cdk2, and p27.
It also mediates cell survival during DNA damage, supporting proper cell cycle progression.
Multiple isoforms exist due to alternative splicing.
The SPDYA gene maps to human chromosome 2, which encodes over 1,400 genes and comprises nearly 8% of the human genome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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