Thermo Fisher Scientific LSM11 Polyclonal Antibody
Human LSM11 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. IHC(P) 실험에 적합하며, 항원 친화 크로마토그래피로 정제됨. PBS/glycerol buffer에 보존되며, 연구용으로만 사용 가능.
- 판매단위
- pk
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Thermo Fisher Scientific LSM11 Polyclonal Antibody
Applications
- Immunohistochemistry (Paraffin) (IHC (P))
Tested Dilution: 1:100–1:200
Publications: -
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Fusion protein of human LSM11 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 40% glycerol |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2636643 |
Product Specific Information
This antibody detects endogenous levels of total LSM11 protein.
Target Information
LSm11 is a 360 amino acid protein localized in the nucleus and belongs to the LSm subfamily of snRNP Sm proteins. It contains an N-terminal domain necessary for pre-mRNA cleavage and binds specifically to U7 snRNA, playing a role in cell cycle regulation and cell growth.
The LSm11 gene is located on human chromosome 5, which spans about 181 million base pairs (≈6% of the human genome). Deletion of the p arm of chromosome 5 causes Cri du chat syndrome, while deletion of the q arm or the entire chromosome 5 is associated with therapy-related acute myelogenous leukemia and myelodysplastic syndrome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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