Thermo Fisher Scientific FMO1 Polyclonal Antibody

Applications

Western Blot (WB)

• Tested Dilution: 1:500–1:3,000
• Publications: -

Product Specifications

Product Specific Information

• Recommended positive controls: 293T, A431, H1299, HeLaS3, HepG2, Molt-4, Raji
• Predicted reactivity: Mouse (83%), Rat (82%), Dog (88%), Pig (86%), Rabbit (85%), Rhesus Monkey (98%), Bovine (85%)
• Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Target Information

Metabolic N-oxidation of the diet-derived amino-trimethylamine (TMA) is mediated by flavin-containing monooxygenase and is subject to an inherited FMO3 polymorphism in humans, resulting in a small subpopulation with reduced TMA N-oxidation capacity known as fish odor syndrome (Trimethylaminuria).
Three forms of the enzyme—FMO1 (fetal liver), FMO2 (adult liver), and FMO3—are encoded by genes clustered in the 1q23–q25 region.
Flavin-containing monooxygenases are NADPH-dependent flavoenzymes that catalyze the oxidation of soft nucleophilic heteroatom centers in drugs, pesticides, and xenobiotics.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.