Thermo Fisher Scientific PCBP4 Polyclonal Antibody
Thermo Fisher Scientific의 PCBP4 폴리클로날 항체는 인간 PCBP4 단백질을 인식하며, Western blot과 Immunocytochemistry에 적합합니다. 항원 친화 크로마토그래피로 정제되었고, PBS/glycerol 버퍼에 보관됩니다. 연구용으로만 사용 가능합니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human PCBP4 (Recombinant protein control fragment, Product #RP-105083) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.05 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2663023 |
Product Specific Information
Immunogen sequence:
ATIPYHPSLSL GTVLLSANQG FSVQGQYGAV TPAEVTKLQQ LSSHAVPFAT PSVVPGLDPG TQTSSQEFLV P
Highest antigen sequence identity to the following orthologs:
- Mouse: 96%
- Rat: 96%
Target Information
MCG10 (also known as PCBP4) is a member of the KH-domain RNA-binding protein family, also referred to as alpha-CPs. These proteins bind RNA with specificity for C-rich pyrimidine regions and are involved in post-transcriptional regulation. MCG10 is induced by p53 and DNA damage, leading to apoptosis and G2-M cell cycle arrest. Decreased expression of certain isoforms has been observed in lung cancer, suggesting a tumor suppressor role. Multiple alternatively spliced isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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