Thermo Fisher Scientific GPR120 (extracellular) Polyclonal Antibody

Applications

Western Blot (WB)

• Tested Dilution: 1:200

Flow Cytometry (Flow)

• Tested Dilution: 2.5 µg/0.5×10^6 cells

Product Specifications

Product Specific Information

• Reconstitute antibody with 50 µL of double distilled water (DDW).
• Store reconstituted solution at 4°C for up to 1 week.
• For longer storage, aliquot and keep at -20°C.
• Avoid repeated freeze-thaw cycles.
• Centrifuge antibody preparations before use (10,000 × g, 5 min).

Peptide sequence: (C)RTHFPFF SDVKGDHR
Homology: Rat amino acid residues identical; human – 14/15 amino acid residues identical.

Target Information

An EST for GPR120 has been isolated from a human colon cancer library.
G-protein Coupled Receptors (GPCRs) are one of the largest families of signaling molecules, sharing a seven membrane-spanning helix structure and existing in active/inactive forms.
Activation leads to signaling via G-proteins and downstream effectors.
Negative regulation mechanisms also play key roles in physiological processes and pharmacological research.
GPCR-targeted drugs such as Zyprexa (Eli Lilly) and Claritin (Schering-Plough) are major examples with significant market impact.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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