Thermo Fisher Scientific TMEM173 Polyclonal Antibody
TMEM173(STING) 단백질을 인식하는 Rabbit Polyclonal 항체로, IHC, ICC/IF, ELISA 등 다양한 응용에 사용 가능. Human, Mouse, Rat 시료에 반응하며 Protein A로 정제됨. 1 mg/mL 농도의 액상 형태로 -20°C 보관.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:400 |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from human TMEM173, amino acids 231–330 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage conditions | -20°C |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Target Information
STING is a 379 amino acid signaling protein that acts as a key component of innate immune signaling. It activates NF-kappa-B and IRF3 transcription pathways to induce type I interferons (IFN-alpha and IFN-beta), establishing an antiviral state. STING may also participate in translocation and apoptotic signaling through interactions with MHC-II, facilitating detection of intracellular viral RNA and B-form DNA. It mediates death signaling via ERK pathway activation and is localized in the endoplasmic reticulum membrane, cell membrane, and mitochondrial outer membrane. STING is ubiquitously expressed in most tissues.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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