Thermo Fisher Scientific APOB48R Monoclonal Antibody (OTI1B5)
인체 APOB48R 단백질을 인식하는 마우스 단클론 항체로, Western blot 및 IHC(P) 실험에 적합합니다. 고순도 친화 크로마토그래피 정제, 액상 형태로 제공되며 안정적인 PBS/BSA/glycerol 버퍼에 보존됩니다. 연구용으로만 사용 가능합니다.
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Thermo Fisher Scientific APOB48R Monoclonal Antibody (OTI1B5)
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1B5 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 780–1088 of APOBR produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2723890 |
Target Information
Macrophage receptor that binds to the apolipoprotein B48 (APOB) of dietary triglyceride-rich lipoproteins (TRL) or to a similar domain of APOB in hypertriglyceridemic very low density lipoprotein (HTG-VLDL). It binds and internalizes TRL when outside the context of macrophages, possibly providing essential lipids to reticuloendothelial cells. May also be involved in foam cell formation under elevated TRL and remnant lipoprotein (RLP) conditions. Mediates rapid, high-affinity uptake of chylomicrons (CM), HTG-VLDL, and trypsinized VLDL devoid of APOE in vitro.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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