Thermo Fisher Scientific MTCH2 Polyclonal Antibody
MTCH2 단백질을 인식하는 Rabbit Polyclonal Antibody로, Western blot, IHC, ICC/IF, ELISA 등 다양한 응용에 적합합니다. Human, Mouse, Rat에 반응하며, Protein A로 정제된 1 mg/mL 액상 형태입니다. 세포자멸사 연구에 유용합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:100–1:500 |
| Immunohistochemistry (Frozen) (IHC-F) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from human MTCH2 (amino acids 210–303) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | –20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
MTCH2 is a member of the mitochondrial carrier protein family that catalyzes the exchange of substrates across the inner mitochondrial membrane. It is targeted by Bid, a pro-apoptotic Bcl-2 family member, in response to apoptotic signals, suggesting that MTCH2 may play a key role in the mitochondrial apoptosis pathway. Apoptosis is essential for normal organism development, tissue homeostasis, and removal of damaged cells. Disruption of this process has been implicated in diseases such as cancer. The Bcl-2 family includes regulators of apoptosis that either inhibit or promote cell death.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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