Thermo Fisher Scientific CHUK Monoclonal Antibody (4D11)
CHUK 단백질을 표적으로 하는 Thermo Fisher Scientific의 단클론 항체. Western blot, ICC/IF, ELISA에 사용 가능. Human 시료 반응성, Mouse IgG1 isotype. Affinity chromatography로 정제된 액상 항체로, 보존제 무첨가. 연구용으로만 사용.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–5 µg/mL |
| Immunocytochemistry (ICC/IF) | 10 µg/mL |
| ELISA | 0.03 ng/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 4D11 |
| Immunogen | CHUK (NP_001269, 646–745 a.a.) partial recombinant protein with GST tag (GST tag MW: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
RQKEIWHLLK IACTQSSARS LVGSSLEGAV TPQTSAWLPP TSAEHDHSLS CVVTPQDGET SAQMIEENLN CLGHLSTIIH EANEEQGNSM MNLDWSWLTE
Target Information
CHUK (IKK alpha) is a serine/threonine kinase involved in signal transduction and cellular communication.
It belongs to the cytokine-activated protein complex that inhibits the NF-kappa B complex.
IKK alpha, together with IKK beta and the regulatory protein NEMO (IKK gamma), phosphorylates IkB proteins, targeting them for ubiquitin-mediated degradation.
This protein plays a critical role in inflammation and cell survival processes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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