Thermo Fisher Scientific TLR8 Polyclonal Antibody
Rabbit polyclonal antibody against human TLR8. Validated for Western blot and immunoprecipitation. Recognizes N-terminal peptide of TLR8. Supplied as liquid at 1 mg/mL. Suitable for innate immunity and pathogen recognition studies.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunoprecipitation (IP) | 4–6 µL/mg lysate |
Product Specifications
| Specification | Detail |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to the N-terminus of Human TLR8 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | Store at 4°C for short term; for long term, store at -20°C. Avoid freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2866814 |
Target Information
The TLR8 protein is a member of the Toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) expressed on infectious agents and mediate cytokine production necessary for effective immune responses. The TLR8 gene is predominantly expressed in lung and peripheral blood leukocytes and is located near TLR7 on the X chromosome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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