Thermo Fisher Scientific SMYD5 Polyclonal Antibody

Applications

Western Blot (WB)

• Tested Dilution: 0.04–0.4 µg/mL
• Publications: -

Immunohistochemistry (Paraffin) (IHC (P))

• Tested Dilution: 1:500–1:1,000
• Publications: -

Product Specifications

Product Specific Information

Immunogen sequence:
MYCSAECRLA ATEQYHQVLC PGPSQDDPLH PLNKLQEAWR SIHYPPETAS IMLMARMVAT VKQAKDKDRW IRLFSQFCNK TANEEEEIVH KLLGDKFKG

Highest antigen sequence identity to orthologs:

• Mouse: 82%
• Rat: 91%

Target Information

Retinoic acid (RA) represents the oxidized form of vitamin A and, via interactions with retinoic acid receptors (RARs), plays a crucial role in development, cellular growth, and differentiation.
The gene encoding RAI15 maps to human chromosome 2, which houses over 1,400 genes and comprises nearly 8% of the human genome.
Harlequin ichthyosis, a rare and morbid skin deformity, is associated with mutations in the ABCA12 gene, while the lipid metabolic disorder sitosterolemia is associated with defects in the ABCG5 and ABCG8 genes.
Additionally, an extremely rare recessive genetic disorder, Alström syndrome, is caused by mutations in the ALMS1 gene, which maps to chromosome 2.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.