Thermo Fisher Scientific AP3M1 Polyclonal Antibody
AP3M1 단백질을 인식하는 Rabbit Polyclonal Antibody로 Western blot 및 IHC(Paraffin)에서 검증됨. 인간, 개, 소 등 다양한 종에 반응. Protein A로 정제된 액상 항체로, 0.5 mg/mL 농도. 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 3–5 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 10 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Bovine, Dog, Chicken, Horse, Hamster, Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Portion of amino acid 140–190 of human AP3M1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2718860 |
Target Information
The AP3 complex is a heterotetramer composed of two large adaptins (AP3D1, AP3B1 or AP3B2), a medium adaptin (AP3M1 or AP3M2), and a small adaptin (APS1 or AP3S2). The complex is associated with the Golgi region as well as peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes.
AP3M1 is highly homologous to AP3M2 but is the preferred binding partner to the YQRL motif from the cytosolic domain of TGN38. AP3M1 has also been shown to interact with the HIV-1 virulence protein Nef.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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