Thermo Fisher Scientific ADSL Monoclonal Antibody (OTI2D10), TrueMAB
ADSL 단백질을 인식하는 Mouse monoclonal 항체로 Western blot, IHC, Flow Cytometry에 사용 가능. 인간, 개, 랫트 반응성. 고순도 친화 크로마토그래피 정제. -20°C 보관, 연구용 전용.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
| Flow Cytometry (Flow) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Dog, Human, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2D10 |
| Immunogen | Full length human recombinant protein of human ADSL produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.55 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
ADSL (adenylosuccinate lyase), also known as AMPS, ASL, or ASASE, is a 484-amino acid enzyme involved in purine biosynthesis and AMP formation from inosine monophosphate. It catalyzes key reactions in AMP biosynthesis, including removal of fumarate from SAICA ribotide to produce AICA ribotide, and from adenylosuccinate to yield AMP.
Mutations in the ADSL gene cause adenylosuccinase deficiency, an autosomal recessive disorder characterized by epilepsy, growth retardation, and muscular wasting. Multiple isoforms exist due to alternative splicing.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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