Thermo Fisher Scientific TRAP220 Polyclonal Antibody
TRAP220/MED1 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot, IHC, ICC/IF에 적합합니다. 인간, 마우스, 랫트에 반응하며, 고순도 친화 크로마토그래피 정제. PBS/glycerol buffer에 보관되며 연구용으로 사용됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human MED1 (Accession Q15648), corresponding to amino acid residues Y1431–S1481 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2854172 |
Product Specific Information
This antibody detects endogenous levels of total TRAP220/MED1.
Target Information
TRAP220 (also known as MED1) is a component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. The Mediator functions as a bridge conveying information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. It is recruited to promoters through direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and general transcription factors.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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