Thermo Fisher Scientific PSMD10 Polyclonal Antibody
Thermo Fisher Scientific의 PSMD10 Polyclonal Antibody는 인간 Gankyrin 단백질을 인식하는 토끼 IgG 항체로, WB, IHC, ICC/IF에 사용 가능. 항원 친화 크로마토그래피로 정제된 1 mg/mL 액상 형태이며, TBS 버퍼와 글리세롤 포함. 세포질 및 핵 위치 단백질 검출에 적합.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:600 |
| Immunocytochemistry (ICC/IF) | 1:200 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein within human Gankyrin (aa 1–226) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | TBS, pH 7.4, with 50% glycerol, 0.2% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2913461 |
Product Specific Information
- Positive Control: A549 cell lysate, Hela cell lysate, 293T cell lysate, Hela, SH-SY5Y, human skin tissue
- Subcellular Location: Cytoplasm, Nucleus
Target Information
The 26S proteasome is a multicatalytic proteinase complex composed of a 20S core and a 19S regulator.
The 20S core consists of 4 rings of 28 non-identical subunits (two rings of 7 alpha and two rings of 7 beta subunits).
The 19S regulator includes a base with ATPase and non-ATPase subunits and a lid with up to 10 non-ATPase subunits.
Proteasomes are abundant in eukaryotic cells and cleave peptides in an ATP/ubiquitin-dependent, non-lysosomal pathway.
The immunoproteasome plays a role in processing class I MHC peptides.
This gene encodes a non-ATPase subunit of the 19S regulator, with two transcript isoforms and pseudogenes on chromosomes 3 and 20.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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