Thermo Fisher Scientific Lambda Light Chain Recombinant Mouse Monoclonal Antibody (rLLC, 1738)
인간 람다 라이트 체인을 인식하는 재조합 마우스 단클론 항체로, IHC(P) 등 다양한 면역염색에 적합. HEK293 세포에서 발현되었으며, Protein A/G로 정제된 고순도 항체. PBS(pH 7.4) 용액 형태로 제공되며, 보존제 무첨가. 연구용으로만 사용 가능.
- 카탈로그번호
- 3535-MSM9-P1ABX
- 판매단위
- pk
카탈로그
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Thermo Fisher Scientific Lambda Light Chain Recombinant Mouse Monoclonal Antibody (rLLC, 1738)
Applications
- Immunohistochemistry (Paraffin) (IHC (P))
Tested Dilution: 1–2 µg/mL
Publications: -
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | rLLC, 1738 |
| Immunogen | Recombinant full-length human lambda light chain |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C or -80°C if preferred |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Immunohistochemistry (PFA fixed): incubate antibody for 30 min at room temperature.
Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C, followed by cooling at room temperature for 20 minutes.
Target Information
Immunoglobulin classes share a basic structure of four polypeptide chains: two heavy chains and two light chains (kappa and lambda, each ~22.5 kDa).
Kappa and lambda light chains have variable and constant regions, distinguishable by antigenic properties of the constant region.
The typical ratio of kappa to lambda is 70:30.
Antibodies to kappa light chain are useful for identifying leukemias, plasmacytomas, and certain non-Hodgkin’s lymphomas.
Demonstration of clonality in lymphoid infiltrates indicates malignant proliferation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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