Thermo Fisher Scientific CRLF1 Monoclonal Antibody (4F4)
CRLF1 단백질을 인식하는 Mouse monoclonal antibody(클론 4F4)로, Western blot, ELISA, Immunoprecipitation에 사용 가능. Human 시료에 반응하며, Affinity chromatography로 정제된 액상 제품. 연구용으로만 사용.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–5 µg/mL |
| ELISA | 0.03 ng/mL |
| Immunoprecipitation (IP) | 1–5 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 4F4 |
| Immunogen | CRLF1 (NP_004741, 135 a.a. ~230 a.a) partial recombinant protein with GST tag (GST tag MW: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
PEKPVNISCW SKNMKDLTCR WTPGAHGETF LHTNYSLKYK LRWYGQDNTC EEYHTVGPHS CHIPKDLALF TPYEIWVEAT NRLGSARSDV LTLDIL
Target Information
CRLF1 encodes a member of the cytokine type I receptor family. The protein forms a secreted complex with cardiotrophin-like cytokine factor 1 and acts on cells expressing ciliary neurotrophic factor receptors. The complex can promote survival of neuronal cells. Mutations in this gene result in Crisponi syndrome and cold-induced sweating syndrome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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