Thermo Fisher Scientific CD68 Monoclonal Antibody (KP1)

Applications

Tested Dilution

Publications

Western Blot (WB)

-

View 1 publication 1 publication

Immunohistochemistry (IHC)

-

View 108 publications 108 publications

Immunohistochemistry (Paraffin) (IHC (P))

1 µg/mL

View 6 publications 6 publications

Immunohistochemistry (Frozen) (IHC (F))

-

View 2 publications 2 publications

Immunocytochemistry (ICC/IF)

5 µg/mL

View 7 publications 7 publications

Flow Cytometry (Flow)

-

View 1 publication 1 publication

Product Specifications

Species Reactivity

Cat, Human, Non-human primate, Rat

Published species

Cynomolgus monkey, Hamster, Human, Mouse, Pig, Rabbit, Rat, Rhesus monkey

Host/Isotype

Mouse / IgG1, kappa

Class

Monoclonal

Type

Antibody

Clone

KP1

Immunogen

Subcellular fraction of human alveolar macrophages if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:CD68,uniProtId:P34810-1,ncbiNodeId:9606,antigenRange:1-354,antigenLength:354,antigenImageFileName:MA5-13324_CD68_P34810-1_House_mouse.svg,antigenImageFileNamePDP:MA5-13324_CD68_P34810-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

View additional formats

• Alexa Fluor 420
• Alexa Fluor 514
• Alexa Fluor 700
• Alexa Fluor Plus 488
• Alexa Fluor Plus 555
• Alexa Fluor Plus 647
• Alexa Fluor Plus 750
• Request custom conjugation

Form

Liquid

Concentration

0.5 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.2

Contains

0.09% sodium azide

Storage conditions

4° C

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_10987212

Product Specific Information

MA5-13324 targets CD68 in IHC (P) and ICC/IF applications and shows reactivity with Feline, Human, Non-human primate, and Rat samples. Does not react with Canine or Chicken.

The MA5-13324 immunogen is subcellular fraction of human alveolar macrophages.

Target Information

CD68 (Macrosialin) is a 110 kDa integral membrane glycoprotein predominantly expressed on the intracellular lysomsomes of monocytes and macrophages and to a lesser extent by dendritic cells and peripheral blood granulocytes. Also, CD68 could play a role in phagocytic activities of tissue macrophages, both in intracellular lysosomal metabolism and extracellular cell-cell and cell-pathogen interactions. CD68 is expressed by interdigitating reticulum cells in tonsil and some histiocytic lymphoma or histiocytosis, acute myeloid leukemia (AML), and granulocytic sarcoma. Elevated expression of CD68 has been demonstrated on CD34+ cells in various human malignancies, including several Acute Myeloid Leukemia studies.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.