Thermo Fisher Scientific CD10 Polyclonal Antibody
CD10 단백질을 인식하는 Rabbit Polyclonal 항체로, WB, IHC, ICC, ELISA 등 다양한 응용에 사용 가능. Human, Mouse, Rat 시료에 반응하며, 고순도 친화 크로마토그래피 정제. 연구용으로만 사용.
- 카탈로그번호
- NEPR-151AP
- 판매단위
- pk
카탈로그
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (IHC) | 1:50–1:250 |
| Immunocytochemistry (ICC/IF) | 1:50–1:250 |
| ELISA | 1:10,000 |
| Immunoprecipitation (IP) | 1:50–1:250 |
| Immunomicroscopy (IM) | 1:50–1:200 |
Product Specifications
| Item | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Multi-epitope synthetic peptides (mixture used for NEPR-101AP, NEPR-112AP, NEPR-121AP, NEPR-131AP, NEPR-141AP) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5–1.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | Proprietary buffer, pH 7.4–7.8, with 30% glycerol, 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | –20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
CD10 (Common Acute Lymphocytic Leukemia Antigen, CALLA) is a cell surface enzyme with neutral metalloendopeptidase activity that inactivates a variety of biologically active peptides. It is expressed on lymphoblastic, Burkitt’s, and follicular germinal center lymphoma cells, immature B cells in adult bone marrow, and cells from patients with chronic myelocytic leukemia (CML). CD10 is also present on breast myoepithelial cells, bile canaliculi, fibroblasts, and highly expressed on the brush border of kidney and gut epithelial cells.
This 100 kDa type II transmembrane glycoprotein cleaves peptides at the amino side of hydrophobic residues and inactivates several peptide hormones, including glucagon, enkephalins, substance P, neurotensin, oxytocin, and bradykinin. The CD10 gene has a 5′ untranslated region that is alternatively spliced, generating four mRNA transcripts without affecting the coding region. Diseases associated with CD10 dysfunction include Spinocerebellar Ataxia 43 and Charcot-Marie-Tooth Disease.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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